Endocrine Abstracts

It is widely accepted that, in addition to serving as a repository for energy reserves, adipose tissue is an active endocrine organ that secretes a variety of signalling molecules, the adipokines, which play important roles in the regulation of metabolism, energy balance, feeding behaviour, vascular homeostasis and immunity. In particular, leptin, resistin and adiponectin have been implicated in energy and glucose homeostasis. Additional neuroendocrine functions have also been...

IntroductionAlthough surgical treatment of acromegaly is the treatment of choice in most patients, a wide therapeutic arsenal is available. Medical treatment can be indicated as primary treatment, complementary and even as pre-operative treatment.ObjectivesTo determine the prevalence of uncured acromegaly and the prevalence of controlled disease within this group. To clinically, biochemically and histological...

BackgroundAcromegaly is an infrequent chronic multisystemic disease associated with a significant morbidity and mortality rate. The treatment of choice is transsphenoidal surgery (TSS) because of its low risk of mortality and few complications.AimsTo determine the cure prevalence after TSS of growth hormone (GH) secreting pituitary adenomas. To analyze the predictive factors of non-remission after the surgery...